After many tries to get PDK 9.5.1. set up on my Mac (upgrading from PDK 9.3 and ActivePerl 5.18) I finally uninstalled all ActivePerl versions and PDK, including Library/Application Support, preferences, emptied caches etc. I reinstalled ActivePerl and the PDK, but still no go.
The GUI returns the following error at launch: '/usr/bin/perl' has inconsistent binexp value in Config.pm
The command line app returns this message: Panic: Some symbols not resolvable from /usr/local/ActivePerl-5.22/lib/CORE/libperl.dylib
perl -v returns: This is perl 5, version 22, subversion 2 (v5.22.2) built for darwin-thread-multi-2level
perlapp-gui -v returns: perlapp-gui 9.5.1 build 300018
Perl itself works fine and the same setup works also with Windows.