What version of ActivePython will work with my Mac with an Intel processor?
The first version of ActivePython to be built natively for Intel Macs was ActivePython 2.4.2.10. Versions before this version were built specifically for PowerPC-based Macs. It may be possible to run the PowerPC version on the Intel Macs, taking advantage of the PowerPC emulation layer in OS X; however, this tends to be quite slow. Therefore, we recommend only using the Intel-specific builds of ActivePython 2.4.2.10 or higher on an Intel Mac.
For each build of ActivePython 2.4.2.10 and higher there are two files. One file specifies macosx-powerpc, and is of course the build for PowerPC-based Mac OS X systems. The other file specifies macosx-x86, and is the correct package to install on your Intel Mac.